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Professor of organic chemistry. Curriculum - Department of Organic Chemistry of the Russian University of Chemical Technology named after. Profile: “Nanoengineering for chemistry, pharmaceuticals and biotechnology”

NEW PROFILE FOR BACHELOR TRAINING

Direction of preparation:

03/18/01 “Chemical technology”

Profile:

"Chemical technology of oil and gas processing"

Qualification– Bachelor

Graduates receive a state bachelor's diploma

Form and terms of training– full-time (4 years), part-time (5 years).

Training is free and also on a contract basis.

From September 1, 2017 at NI RKHTU named after. D.I. Mendeleev opens a new profile for bachelor’s training - within the framework of the training direction 03/18/01. "Chemical Technology". The oil and gas industry is one of the leading sectors of the economy of our country. This is due not only to large volumes of natural oil and gas reserves, but primarily to their processed products, without which it is difficult to imagine our daily lives today. These are operating materials (fuels, oils, lubricants, etc.) for all types of transport and mechanical engineering equipment, energy resources, medicines, polymer materials, synthetic fibers, varnishes, paints, detergents and cosmetics and much, much more. Therefore, the prospects for studying in this profile and subsequent employment should not raise any doubts. Potential employers can include the largest oil and gas industry enterprises Lukoil, TNK, Rosneft, Gazprom, SIBUR, as well as other companies and organizations involved in the problem of oil and gas refining. You may also be in demand in other areas of activity related to organic chemistry - the basis of deep processing of oil and gas in order to obtain substances with useful properties. These are primarily industrial enterprises in the petrochemical and gas industries, the synthesis of new organic compounds, marketing of the petrochemical products market , as well as research institutes, higher education institutions, etc.

Training of bachelors according to the profile "Chemical technology of oil and gas processing" carried out at the Department of Chemical Technology of Organic Substances and Polymer Materials. The educational process is conducted by highly qualified teachers, 90% of whom have academic degrees and titles. These are mainly graduates of our institute with a specialty in “Technology of Basic Organic and Petrochemical Synthesis.” We have modern equipment for conducting educational process and scientific research. Modern computer technologies are widely used. All this allows us to train specialists who meet modern requirements in the field of chemical technology of oil and gas processing.

Currently, our applicants, as well as foreign students (Iraq, Yemen, Turkmenistan) of the preparatory faculty of NI RKhTU, are already showing great interest in the new profile.

THE DEPARTMENT CONTINUES TRAINING IN THE PROFILE

"Chemical Technology organic matter»

Direction of training :

03/18/01 “Chemical technology”

Qualification– Bachelor

Graduates receive a state bachelor's diploma

Form and terms of training – full-time (4 years), part-time (5 years).

Training is free and also on a contract basis.

The department was founded in 1963, has graduated more than a thousand specialists in the field of technology for the production of organic substances, has modern educational and scientific laboratories, all teachers of the department have academic degrees and titles.


Having completed four years of training in the profile: “ Chemical technology of organic substances"and, having received a bachelor's qualification, you will be able to work in the following areas:

  • highly efficient, environmentally friendly, energy- and resource-saving technologies of organic synthesis
  • synthesis of new organic substances, including medicines, active components of detergents and cosmetics,
  • marketing of the market for petrochemical products and chemical technologies,
  • engage in research work in the field of organic chemistry, catalysis and kinetics of organic reactions at any institute in the country, completing and defending candidate and doctoral dissertations.

Graduates of our department can work in a variety of fields related to organic chemistry as specialists:

  • Chemical engineer-technologist.
  • Chemist doing research for industry.
  • Chemist responsible for product quality control.
  • Sales representative, sales consultant.
  • Forensic chemist.
  • Environmental chemist.
  • Expert in the preservation of historical art objects.
  • Chemist-teacher.
  • Synthetic chemist
  • Chemist-scientist

Here is a far from complete list of enterprises and organizations where our graduates work: AZOT MCC "EUROCHEM", OJSC "Procter & Gamble", LLC "NIAP-CATALYSOTOR", LLC "POLIPLAST (Novomoskovsk), OJSC "Plastik", (Novomoskovsk) Uzlovaya), JSC Khimvolokno, JSC Shchekinoazot (Shchekino), Efremov synthetic rubber plant, OJSC Severstal (Cherepovets), higher educational institutions (Moscow, St. Petersburg, Tula, Novomoskovsk), research institutes (Moscow, Novosibirsk), etc.

Speciality "Chemical technology of organic substances"- it's not just an excellent education, this is a guaranteed success both in the chemical industry and in research activities - which means a feeling of confidence in oneself and the future!

History of the department

The Department of Organic Chemistry and Macromolecular Compounds was formed in 2009 as a result of the merger of the Departments of Organic Chemistry and Macromolecular Compounds.

Currently, the department has 12 teachers: 6 doctors of science, professors, 6 candidates of science, associate professors and 5 staff, of which 3 are candidates of chemical sciences.

The head of the department is Khashirova S.Yu. The department trains students in the specialty “Fundamental and Applied Chemistry”, specialization “Organic Chemistry”, bachelor’s degree in “Chemical Technology”, master’s degree in the program “Chemical Technology”, “High Molecular Compounds”.

To train highly qualified personnel in the field of synthesis, modification, and research of the properties of high-molecular compounds (polymers), postgraduate and doctoral studies are functioning in the department of “High-Molecular Compounds”. Currently, the department has 2 doctoral students, 11 graduate students and 41 master's students. Of no small importance in the training of specialists for the national economy is research work, which the department carries out in 8 areas. The teaching staff has repeatedly won grants from various foundations at competitions.

The department regularly holds All-Russian and international conferences, where students, masters, graduate students and doctoral students specializing in the department take an active part. The I-XI International Conference “New Polymer Composite Materials” was organized and held with the participation of leading Russian scientists. The 1-6 All-Russian Conference “Nanostructures in Polymers and Nanocomposites” was held, where leading scientists from universities and institutes of the Russian Academy of Sciences took part. Employees of the department often travel abroad to participate in International symposia and conferences (USA, France, Switzerland, Germany, Spain, Mexico). The department constantly maintains contacts with the Russian Chemical Technical University named after. D. I. Mendeleev, FSUE NIIFKHI im. Karpov, INEOS named after. N.N. Nesmeyanov RAS, Institute of Chemical Art named after. A.V. Topchiev RAS, Ivanovo University of Chemical Technology, which gives students, masters, graduate students and doctoral students the opportunity to travel to carry out various research.

Main activities

  • In-depth study of ways to optimize and intensify the processes of targeted synthesis of macromolecules, and, consequently, targeted regulation of the complex of properties of synthesized polymers.
  • Targeted synthesis of new condensation polymers of various structures (macromolecular design).
  • Directed regulation of a complex of valuable properties of synthesized polymers (high chemical, thermal and heat resistance, large coke residue, good electrical properties, physical and mechanical properties, etc.).
  • Development of technology for the production and introduction of various stabilizers (modifiers) into the polymer matrix. Assessment of the stabilizing and modifying influence of additives on the basic properties of polycondensation polymers in the melt and in the solid phase.
  • Carrying out a complex of physical and chemical studies with the aim of purposefully changing the “structure-property” relationships depending on the nature of the modifiers.
  • Synthesis of new polyelectrolytes and research into the possibility of obtaining new biologically active and biocidal substances based on them.
  • Development of technology for producing new polymer composite nanomaterials based on water-soluble ionic polymers and layered silicates to create products with sorption and biocidal properties.
  • Development of fireproof polymer composites and nanocomposites for the cable industry.
  • Development of polymer materials with increased barrier properties.
  • Development of theoretical foundations and technology for the production of aromatic superstructural polymers and composite materials based on them, with improved operational and technological characteristics.
  • Development of new polymer materials for digital design and production (3D printing).
  • Creation, together with enterprises of the real sector of the economy, of high-tech production of new polymer products based on developed technologies.

Composition of the department:

  1. Khashirova Svetlana Yurievna – Doctor of Chemical Sciences, Head. Department of Organic Chemistry and Macromolecular Compounds.
  2. Bazheva Rimma Chamalovna – Doctor of Chemical Sciences, Professor of the Department of Organic Chemistry and Macromolecular Compounds
  3. Begieva Madina Bilyalovna – Doctor of Chemical Sciences, Professor of the Department of Organic Chemistry and Macromolecular Compounds
  4. Borukaev Timur Abdulovich – Doctor of Chemical Sciences, Professor of the Department of Organic Chemistry and Macromolecular Compounds
  5. Leana Khasanovna Kuchmenova – Ph.D., senior lecturer at the Department of Organic Chemistry and Macromolecular Compounds.
  6. Musaev Yuri Israfilovich – Doctor of Chemical Sciences, Professor of the Department of Organic Chemistry and Macromolecular Compounds
  7. Musaeva Eleonora Borisovna – Ph.D., Associate Professor of the Department of Organic Chemistry and Macromolecular Compounds.
  8. Kharaev Arsen Mukhamedovich – Doctor of Chemical Sciences, Professor of the Department of Organic Chemistry and Macromolecular Compounds
  9. Khochuev Idris Yusufovich – Ph.D., Associate Professor of the Department of Organic Chemistry and Macromolecular Compounds.
  10. Ardasheva Almira Abdul-Kerimovna – engineer of the Department of Organic Chemistry and Macromolecular Compounds
  11. Gevorkova Areknaz Surenovna – leading engineer of the Department of Organic Chemistry and Macromolecular Compounds
  12. Kazancheva Fatimat Krymovna – Ph.D., engineer of the Department of Organic Chemistry and Macromolecular Compounds
  13. Kozhemova Karina Ruslanovna – Ph.D., Engineer, Department of Organic Chemistry and Macromolecular Compounds
  14. Kharaeva Ruzanna Alekseevna – Ph.D., engineer of the 1st category of the Department of Organic Chemistry and Macromolecular Compounds

The department is graduating in the field of training 03/18/01 – Chemical technology, profile “Technology and processing of polymers”, 05/04/01 Fundamental and applied chemistry, specialization “Organic chemistry”, 04/18/01 Chemical technology, master’s program “Technology and processing of polymers”, 04.04.01 Chemistry, master's program “High molecular compounds”.

Scientific research

Main directions and forms of activity.

Research activities: conducting scientific research in fundamental and applied areas in the field of chemistry and technology of macromolecular compounds.

Innovation and implementation activities: solving applied problems, design developments, implementation of scientific research results into practice and the educational process.

Educational activities: organization and provision of research work and educational practices for students, undergraduates and graduate students of natural science faculties, provision of additional educational services under individual programs for retraining and advanced training of specialists.

The priority areas of scientific and innovative activity are:

a) fundamental problems of the chemistry of macromolecular compounds;

b) polymer nanocomposites and multilayer structures;

c) physical and chemical methods for studying polymer composites and nanomaterials;

d) modification and stabilization of polymer materials;

e) recycling and disposal of polymer composite materials and products made from them;

f) theoretical modeling of the structure and properties of polymer composite materials;

g) new polymer materials: synthesis and properties.

Qualitative indicators of the department

Employees of the department have published more than 2,000 articles in foreign and domestic journals, 30 monographs have been published: 4 were published in the USA, one of them received funding by participating in the competition of the Russian Foundation for Basic Research. According to the profile of the department, there is a Council for the defense of doctoral and candidate dissertations “High molecular compounds”. The department has created all the conditions (scientific potential, material and technical base, availability of instruments, postgraduate studies, dissertation council, etc.) in order to go from student to professor within KBSU. The department operates a scientific and educational center “Polymers and Composites” and a Laboratory of Progressive Polymers. The department’s staff has obtained a number of original scientific results in the field of polycondensation polymers of various classes, which have received international recognition and are supported within the framework of the Federal Target Program “Research and development in priority areas of the scientific and technological complex of Russia (GK No. 02.552.11.7079; No. 2.513.11.3158; No. 02.513. 11.3219; No. 02.740.11.5121, No. 02.740.11.0798); Analytical departmental target program “Development of the scientific potential of higher education (2009-2010)” Civil Code No. 2.1.1/3612; RFBR project (06-03-96641). The results of several projects carried out with the participation of KBSU on orders from organizations in the real sector of the economy were implemented at enterprises in the industry. The technology for producing nanocomposite multilayer films from polyethylene was introduced at Yug-Polymer LLC (Stavropol Territory, Kislovodsk), the technology for producing polybutylene terephthalate was introduced at the Republican Unitary Enterprise PO Mogilevkhimvolokno (Belarus). Work was successfully carried out to create nanocomposite cable products with increased fire resistance together with CJSC Kavkazkabel Cable Plant within the framework of Decree No. 218 of the Government of the Russian Federation under agreement No. 13.G25.31.0048 dated September 7, 2010. The project was implemented jointly with TANNETA LLC on “Development and development of high-tech and energy-efficient production of functional modifying composites and new generation preforms based on them for the production of import-substituting, environmentally friendly polyethylene terephthalate containers with increased barrier properties” (agreement No. 02.G25.31.0008 dated February 12, 2013).

Masters, graduate students and doctoral students of the department have repeatedly received scholarships from the President of the Russian Federation and the KBR, received grants through the DAAD, under the U.M.N.I.K. program. During the existence of the department, which provides training in high-molecular compounds by the teaching staff, headed by the founder and head of the Scientific School under the leadership of Mikitaev A.K. 35 doctors of science and more than 100 candidates of science were trained.

This is one of the oldest departments of the Faculty of Chemistry, founded in 1869. Outstanding chemists worked here, whose names make up the glory of Russian science - A.M. Butlerov, N.A. Menshutkin, A.E. Favorsky, S.V. Lebedev. In the post-revolutionary years, the department was headed by professors Konstantin Aleksandrovich Taipale, Boris Nikolaevich Dolgov, Ivan Aleksandrovich Dyakonov, Konstantin Aleksandrovich Ogloblin, Anatoly Alekseevich Potekhin, who made a major contribution to the development of organic chemistry.

Since 2007, the department has been headed by Professor Mikhail Anatolyevich Kuznetsov.

Department of Organic Chemistry today

Currently, the educational process at the Department of Organic Chemistry is led by 8 professors (to which, in principle, we must add the director of the Institute of Chemistry I.A. Balov), 9 associate professors, 2 senior teachers and 4 assistants. Among the teachers and staff of the department, 10 people have a Doctor of Chemical Sciences degree, 18 have a Candidate of Sciences degree. The educational work of the department includes general courses and workshops on organic chemistry, introduction to spectroscopy, lectures on physical methods of research of organic substances and stereochemistry of organic compounds, as well as special courses on various sections of synthetic and analytical organic chemistry for masters and graduate students.

The department prepares bachelors and masters in two specializations: general and synthetic organic chemistry, as well as analytical organic chemistry, and is actively involved in the training of graduates within the framework of the interdepartmental specialization - environmental chemistry. Every year about 20 bachelors and masters graduate from the department. Every year, 4–8 graduate students are admitted, most of whom successfully defend their PhD theses on time. Graduates of the department are in great demand in the labor market both in Russia and abroad. Faculty, staff, students and graduate students of the department actively participate in international scientific cooperation. Good scientific contacts have been established with universities in Germany (Karlsruhe, Leipzig, Ulm), Austria (Graz), France (Marseille, Strasbourg), USA (Buffalo, Bowling Green, Los Angeles).

Modern scientific topics of the Department of Organic Chemistry have strong historical roots. Here, first of all, it should be noted that they originated from the works of A.E. Favorsky research in the field of functionalized acetylene and diacetylene derivatives, which are now being intensively carried out in the groups of Prof. I.A. Balova and A.V. Vasilyeva. Pioneering works of prof. I.A. Dyakonov on the chemistry of diazo compounds, carbenes, small cycles were continued and developed in the works of professors M.A. Kuznetsova, A.P. Molchanova, V.A. Nikolaeva, M.S. Novikova, A.F. Khlebnikov and their students. Prof.'s legacy B.V. Ioffe in the field of chemistry of organic derivatives of hydrazine, chemistry of heterocyclic compounds is being developed by prof. M.A. Kuznetsov, Doctor of Chemical Sciences, Associate Professor. V.V. Sokolov, and his analytical topics are enhanced by the works of prof. I.G. Zenkevich and L.A. Kartsova.

Based on the results of the scientific activities of teachers, staff, students and graduate students of the department, about 100 articles are published annually in leading international and domestic journals, dozens of abstracts of reports at international and all-Russian conferences. All-Russian and international conferences on current problems of organic chemistry are regularly held at the department, including youth conferences with wide international participation. The scientific developments of the department are supported by grants from the Russian Science Foundation, the Russian Foundation for Basic Research, grants from the President, the government of St. Petersburg, and international grants. Teachers of the department have repeatedly received prestigious awards from St. Petersburg University "For pedagogical excellence" (A.A. Kartsova, 2005, M.A. Kuznetsov, 2009, M.S. Novikov, 2012) and for the best scientific works (A.F. Khlebnikov, 2011).

Main directions of scientific research

  • Chemistry of unsaturated and strained carbo- and heterocyclic systems. Carbenes, diazo compounds, small rings (azirines, aziridines, diaziridines, cyclopropanes, cyclopropenes, triangulans), framework and spiro-jointed structures, 1,3-dipoles, cycloaddition reactions. Doctor of Chemical Sciences prof. M.A. Kuznetsov, A.P. Molchanov, M.S. Novikov, A.F. Khlebnikov, Ph.D., Associate Professor. A.S. Konev, N.V. Rostovsky, A.S. Pankova, A.V. Stepakov, Ph.D., Art. teacher.. O.A. Tomashenko, Ph.D., ass. HER. Galenko, M.M. Efremova, Ph.D. T.A. Kornilov.
  • Chemistry of reactive intermediate sextet particles, diazo compounds and ylides. Diazocarbonyl and diazodicarbonyl compounds. Photochemistry. Doctor of Chemical Sciences, prof. M.A. Kuznetsov, A.P. Molchanov, V.A. Nikolaev, M.S. Novikov, A.F. Khlebnikov, Ph.D., Associate Professor. A.S. Konev, A.S. Pankova, Ph.D. Ass. Yu.Yu. Medvedev.
  • Chemistry of acetylene and diacetylene derivatives. Synthesis and transformations of functionalized diacetylenes, enediynes, synthesis of new fused heterocycles based on them. Doctor of Chemical Sciences, prof. I.A. Balova, Doctor of Chemical Sciences, Prof. A.V. Vasiliev, Ph.D., Associate Professor I.A. Boyarskaya, N.A. Danilkina, V.N. Sorokoumov, Ph.D., Art. Rev. A.G. Lyapunova, Ph.D., ass. V.N. Mikhailov.
  • Hydrazine derivatives and polynitrogen compounds. Aminoaziridines. Aminonitrenes, azomethine ylides and 1,3-dipolar cycloaddition reactions. Three-, five- and six-membered nitrogen heterocycles. Doctor of Chemical Sciences, prof. M.A. Kuznetsov, Ph.D., Associate Professor. A.S. Pankova.
  • Aziridines, oxiranes, thiiranes, thietanes, amidines, sulfonamides and sultams. Aromatic and non-aromatic heterocyclic compounds containing nitrogen, sulfur and oxygen atoms. Doctor of Chemical Sciences, Associate Professor V.V. Sokolov.
  • Analysis of organic compounds using gas and liquid chromatography, capillary electrophoresis, gas chromatography-mass spectrometry, including studies of the environment, biological objects, and pharmaceuticals. Analysis and separation of mixtures of biologically active compounds using high-performance liquid and thin-layer chromatography, capillary zone electrophoresis, micellar electrokinetic chromatography, development of new options for organic analysis for medical diagnostic purposes. Development of new methods for chromatographic and chromatographic-spectral identification of organic compounds, creation of databases of analytical parameters. Doctor of Chemical Sciences, Prof. I.G. Zenkevich, prof. L.A. Kartsova, Ph.D., Associate Professor. E.A. Bessonova.

More detailed information about the areas of research of various scientific groups can be found at

Ministry of Education and Science of the Russian Federation Federal Agency for Education Russian Chemical and Technological University named after D.I. Mendeleev Approved by: Rector of the Russian Chemical Technology University named after. D.I.Mendeleeva V.A. Kolesnikov “____”____2007 CURRICULUM of the course “FUNDAMENTALS OF BIOCHEMISTRY” Direction 550800 “Chemical technology and biotechnology” for students of all chemical-technological specialties and students of the chemical-pedagogical department (011000) The program is approved by the Methodological Section of the Academic Council of the Russian Chemical Technology University named after. DI. Mendeleev "____"____2007 Chairman Zhilin V.F. Moscow 2007 Explanatory note The course is intended for all students of the Russian Chemical Technical University named after. DI. Mendeleev, studying in the direction of “Chemical technology and biotechnology” and is a logical continuation of all chemical disciplines that are studied by students in the first and second years - the theoretical foundations of chemistry, inorganic chemistry, analytical, physical and organic chemistry. The course introduces students to the basics of biochemistry - the science of chemical processes occurring in living cells and organisms, as well as the biological substrates involved in these processes. The place of biochemistry and its isolated sections in the system of life sciences is considered and characterizes the relationships between biochemistry, organic and bioorganic chemistry. The application of biochemical knowledge in solving chemical, technological, engineering, environmental and social problems is illustrated. The main sections of the course are devoted to the structure and functions of cells and cellular organelles, the structure and biological functions of the most important biopolymers and bioregulators (proteins, nucleic acids, carbohydrates, lipids, vitamins, coenzymes, hormones). Much attention is paid to processes specific to living systems: enzymatic catalysis, metabolism of carbohydrates, proteins and lipids, membrane transport, energy conversion, metabolism of xenobiotics. The distribution of lecture and seminar hours (3-0-4) is given below. To monitor the mastery of the course, it is planned to conduct rating tests. The course ends with a differentiated test. The program was compiled at the Department of Organic Chemistry. The program was compiled by prof. Traven V.F. prof. Lopina O.D. exam or Distribution of training hours by sections of the course Section 1 2 3 4 5 6 7 8 9 10 Name Introduction. Basic principles of cytology Amino acids and proteins Enzymes and vitamins Carbohydrates Lipids Nucleic acids Metabolism and metabolism Energy biochemical cycles Bioregulators Hours of lek. family lab. myself. 2 2 2 2 4 5 2 9 4 2 9 4 2 7 3 1 5 3 1 5 2 2 6 5 3 10 5 3 8 Total 36 18 72 Course content 1. Introduction. Subject of biochemistry. Relationship between biochemistry and related disciplines. Static biochemistry: the study of the chemical composition and structure of substances contained in living organisms. Dynamic biochemistry: the study of metabolic processes as the basis of the activity of living organisms. Basic methods of biochemistry. 2. Basic principles of cytology. Elements of cell theory. Prokaryotes and eukaryotes. Cellular organelles, their structure and functions: nucleus, cytoplasm (ribosomes, mitochondria, lysosomes, endoplasmic reticulum, Golgi complex, hyaloplasm), cell membrane and cytoskeleton. The role of water in cell life. 3. Amino acids and proteins. Amino acids: properties, classification, methods of analysis. Peptide synthesis. Primary structure of proteins. Chemical properties and methods for determining the primary structure of proteins. Intra- and intermolecular interactions that determine the spatial structure of proteins. Secondary, tertiary and quaternary structures. Functions of proteins. Denaturation of proteins. The influence of the hierarchical structure of proteins on their biological properties. Methods for isolating and identifying proteins. Classification of proteins. The role of proteins in nutrition. 4. Enzymes and vitamins. Biomedical significance of enzymes. Nomenclature and classification of enzymes. Structure and catalytic properties of enzymes. Principles of enzymatic catalysis. Quantitative determination of enzymatic activity. The influence of temperature, pH, enzyme and substrate concentrations on the rates of enzymatic reactions. Regulation of enzyme activity: allosteric control, competitive and non-competitive inhibition, covalent modification and genetic control. Coenzymes and cofactors. Vitamins: definition and classification. The structure of vitamins and their role in enzymatic reactions and metabolic processes. Enzyme inhibitors as drugs. 5. Carbohydrates. Biomedical significance of carbohydrates. Photosynthesis of carbohydrates. Classification of carbohydrates and their most important reactions. Deoxy sugars and amino sugars. Disaccharides and polysaccharides: lactose, maltose, sucrose, starch, glycogen, cellulose, chitin. The role of carbohydrates in nutrition. 6. Lipids. Biomedical significance of lipids. Structure and classification of lipids. Saturated and unsaturated acids and their esters. Fats and oils. Glycerides and phosphoglycerides. Sphingolipids. Terpenes and steroids. Structure and properties of cell membranes. Eicosanoids: prostaglandins and leukotrienes. 7. Nucleic acids. Biological significance of nucleic acids. Deoxyribonucleic and ribonucleic acids. Nucleotides. Structure and functions in living organisms. Matrix synthesis reactions and their significance. Transmission of hereditary characteristics. Biosynthesis of proteins. Mutagenesis and hereditary diseases. Determination of nucleotide sequence. Biotechnology and genetic engineering. Bioinformatics. 8. Metabolism and metabolism. Concept of metabolism and metabolic pathways. Catabolism and anabolism. Metabolism of carbohydrates. Regulation of blood glucose (insulin and glucagon). Diabetes. Methods for analyzing glucose in blood and urine. Lipid metabolism. Storage and breakdown of fats. Oxidation and biosynthesis of saturated acids. Metabolism of proteins and amino acids. The relationship between the metabolism of proteins, carbohydrates and lipids. Metabolic regulation problems. Regulation and integration of metabolism in mammals. 9. Energy biochemical cycles. Endergonic and exergonic reactions in a living cell. Metabolism and production of biochemical energy. The role of ATP in energy metabolism. Metabolic pathways and associated reactions. Oxidized and reduced forms of coenzymes. Citric acid cycle. Organization of the respiratory chain. Oxidative phosphorylation. Vitamins are antioxidants. 10. Bioregulators. Classification of bioregulators: hormones, neurotransmitters, drugs and xenobiotics. Hormones as chemical regulators of the endocrine system. Classification of hormones: protein hormones, steroid hormones, amino acid derivatives. Mechanisms of action of hormones. Secondary messengers. Neurotransmitters are chemical regulators of the nervous system. The mechanism of nerve signal transmission and the role of neurotransmitters. Adrenaline and norepinephrine. Acetylcholine, its agonists and antagonists. Histamine and antihistamines. Serotonin, dopamine and antidepressants. Dopamine and drug addiction. Medicines and xenobiotics: mechanisms of action and metabolism. Basic literature: 1. Filippovich Yu.B. Fundamentals of biochemistry. - M.: Agar, 1999 Additional literature: 1. Eliot V., Eliot D. Biochemistry and molecular biology, M. YBB Biomedical Chemistry RAMS, 1999. 2. Musil Y., Novakova O., Kunz K. Modern biochemistry in diagrams. Ed. Mir, Moscow, 1981. 3. Kolman Y., Rem K.-G. Visual biochemistry. Ed. Mir, Moscow, 2000. 4. Leninger A. Fundamentals of biochemistry. Ed. Mir, Moscow, 1985, vol. 1-3.

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